Sulphonamides with Diuretic Activity

Evaluation of neonatal hydronephrosis with diuretic renography

  The common use of maternal ultrasonography has increased the apparent incidence of neonatal hydronephrosis. Many of these cases are found to have partial obstruction at the ureteropelvic junction (UPJ). These patients are safely managed in our institution with careful observation and only occasionally require surgical intervention. The authors present two contrastin...

Design, Synthesis and antiHIV activity of Novel Isatine-Sulphonamides

A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integrase inhibitory activity. 4-(1-acetyl-5-methyl-2-oxoindolin-3-ylideneamino)-N-(4,...

Evaluation of Diuretic and Antidiabetic Activity of Esculin

Diuretics are the agents which cause increase in excretion of urine. Diabetes mellitus (DM) is a multi-factorial disorder characterized by hyperglycemia resulting from an increased hepatic glucose production and diminished insulin secretion. The present study was undertaken to study the diuretic and anti-diabetic activity of esculin. Esculin was found to have potent diuretic activity in normal ...

Diuretic Activity of Polyscias Fruticosa (l.) Harms

Polyscias fruticosa (L.) Harm (Family: Araliaceae) is possibly native to Malaysia, but now widely cultivated in tropical areas and as a greenhouse plant. In Fiji, the root is used as a diuretic. The juice from the bark is taken for thrush and an ulcerated tongue or throat. A poultice made from the bark is used on syphilitic sores. The present study was undertaken to investigate diuretic effect ...

Diuretic Activity Studies on Three Medicinal Plants